ID   GHOST(3)-CCR5 DRiP78 and NHERF1 knockdown
AC   CVCL_LI03
DR   cancercelllines; CVCL_LI03
DR   Wikidata; Q54835798
RX   PubMed=26018859;
CC   Population: Caucasian.
CC   Knockout cell: Method=shRNA knockdown; HGNC; HGNC:24581; DNAJC14.
CC   Knockout cell: Method=shRNA knockdown; HGNC; HGNC:11075; NHERF1.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg156Pro (c.467G>C); ClinVar=VCV000634768; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; 1XF1B; GFP (Note=avGFP; original A.victoria green fluorescent protein).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1606; CCR5.
CC   Derived from site: In situ; Bone, right femur; UBERON=UBERON_0000981.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_S491 ! GHOST(3).CCR5
SX   Female
AG   13Y
CA   Cancer cell line
DT   Created: 15-11-17; Last updated: 19-12-24; Version: 15
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RX   PubMed=26018859; PMCID=PMC4790691;
RA   Zhang L., Huang X.-H., Zhou P.-P., Yu G.-L., Yan J., Qin B., Yan X.-G.,
RA   Diao L.-M., Lin P., Kuang Y.-Q.;
RT   "Establishment of HIV-1 model cell line GHOST(3) with stable DRiP78
RT   and NHERF1 knockdown.";
RL   Dong Wu Xue Yan Jiu 36:161-166(2015).
//