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Cellosaurus DT40-ATM(-/-)-RAD5L(-/-) hRad54 (CVCL_LH54)

[Text version]
Cell line name DT40-ATM(-/-)-RAD5L(-/-) hRad54
Synonyms delta-Atm-delta-Rad54+hRad54-DT40; DT40 ATM-/-/RAD54-/- Rad54+
Accession CVCL_LH54
Resource Identification Initiative To cite this cell line use: DT40-ATM(-/-)-RAD5L(-/-) hRad54 (RRID:CVCL_LH54)
Comments Group: Bird cell line.
Knockout cell: Method=Targeted integration; CGNC; 12888; ATM.
Knockout cell: Method=Targeted integration; CGNC; 7881; RAD54L.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:9826; RAD54L.
Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
Cell type: B-cell; CL=CL_0000236.
Disease Chicken bursal lymphoma (NCIt: C134556)
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Breed/subspecies: Hy-Line SC.
Hierarchy Parent: CVCL_1T34 (DT40-RAD54L(-/-))
Sex of cell Female
Age at sampling 1D
Category Cancer cell line
Publications

PubMed=10654944; DOI=10.1093/emboj/19.3.463; PMCID=PMC305583
Morrison C., Sonoda E., Takao N., Shinohara A., Yamamoto K.-i., Takeda S.
The controlling role of ATM in homologous recombinational repair of DNA damage.
EMBO J. 19:463-471(2000)

Cross-references
Cell line collections (Providers) RCB; RCB1651
Cell line databases/resources CLO; CLO_0051494
Encyclopedic resources Wikidata; Q54831470
Entry history
Entry creation15-Nov-2017
Last entry update19-Dec-2024
Version number9