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Cellosaurus K-562-RH (CVCL_LH50)

[Text version]
Cell line name K-562-RH
Accession CVCL_LH50
Resource Identification Initiative To cite this cell line use: K-562-RH (RRID:CVCL_LH50)
Comments Population: Caucasian.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=2446768; DOI=10.1007/BF02797342
Walter H., Al-Romaihi F.A., Krob E.J., Seaman G.V.F.
Fractionation of K-562 cells on the basis of their surface properties by partitioning in two-polymer aqueous-phase systems.
Cell Biophys. 10:217-232(1987)

PubMed=2465826; DOI=10.1007/BF02918374
Walter H., Krob E.J., Al-Romaihi F.A., Johnson D., Lozzio C.B.
Detection of surface differences between closely related cell populations by partitioning. Cultured K-562 cell sublines.
Cell Biophys. 13:173-187(1988)

Cross-references
Encyclopedic resources Wikidata; Q54899221
Entry history
Entry creation15-Nov-2017
Last entry update02-May-2024
Version number12