ID   C57MG/2-69-23
AC   CVCL_LF86
SY   2-69-23
DR   Wikidata; Q54808204
RX   Patent=WO1999043804A1;
RX   PubMed=9488439;
RX   PubMed=11358845;
RX   PubMed=11832495;
CC   Group: Patented cell line.
CC   Characteristics: The expression of the Wnt1 gene is under the control of a tetracycline-repressible promoter.
CC   Transfected with: MGI; MGI:98953; Wnt1.
CC   Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
CC   Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
CC   Breed/subspecies: C57BL/6.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_6824 ! C57MG
SX   Female
AG   23W
CA   Spontaneously immortalized cell line
DT   Created: 15-11-17; Last updated: 29-06-23; Version: 7
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RX   Patent=WO1999043804A1;
RA   Barker N., Korinek V., Clevers H.C.;
RT   "Mouse Tcf-3 and Tcf-4 and tumourigenesis related to wnt/wingless
RT   signalling.";
RL   Patent number WO1999043804A1, 02-Sep-1999.
//
RX   PubMed=9488439; DOI=10.1128/mcb.18.3.1248;
RA   Korinek V., Barker N., Willert K., Molenaar M., Roose J.P., Wagenaar G.,
RA   Markman M., Lamers W., Destree O., Clevers H.C.;
RT   "Two members of the Tcf family implicated in Wnt/beta-catenin
RT   signaling during embryogenesis in the mouse.";
RL   Mol. Cell. Biol. 18:1248-1256(1998).
//
RX   PubMed=11358845;
RA   Szeto W., Jiang W., Tice D.A., Rubinfeld B., Hollingshead P.G.,
RA   Fong S.E., Dugger D.L., Pham T., Yansura D.G., Wong T.A.,
RA   Grimaldi J.C., Corpuz R.T., Singh J.S., Frantz G.D., Devaux B.,
RA   Crowley C.W., Schwall R.H., Eberhard D.A., Rastelli L., Polakis P.,
RA   Pennica D.;
RT   "Overexpression of the retinoic acid-responsive gene Stra6 in human
RT   cancers and its synergistic induction by Wnt-1 and retinoic acid.";
RL   Cancer Res. 61:4197-4205(2001).
//
RX   PubMed=11832495; DOI=10.1074/jbc.M200334200;
RA   Tice D.A., Szeto W., Soloviev I., Rubinfeld B., Fong S.E.,
RA   Dugger D.L., Winer J., Williams P.M., Wieand D., Smith V.,
RA   Schwall R.H., Pennica D., Polakis P.;
RT   "Synergistic induction of tumor antigens by Wnt-1 signaling and
RT   retinoic acid revealed by gene expression profiling.";
RL   J. Biol. Chem. 277:14329-14335(2002).
//