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Cellosaurus C57MG/2-69-23 (CVCL_LF86)

[Text version]
Cell line name C57MG/2-69-23
Synonyms 2-69-23
Accession CVCL_LF86
Resource Identification Initiative To cite this cell line use: C57MG/2-69-23 (RRID:CVCL_LF86)
Comments Group: Patented cell line.
Characteristics: The expression of the Wnt1 gene is under the control of a tetracycline-repressible promoter.
Transfected with: MGI; MGI:98953; Wnt1.
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Parent: CVCL_6824 (C57MG)
Sex of cell Female
Age at sampling 23W
Category Spontaneously immortalized cell line
Publications

PubMed=9488439; DOI=10.1128/mcb.18.3.1248
Korinek V., Barker N., Willert K., Molenaar M., Roose J.P., Wagenaar G., Markman M., Lamers W., Destree O., Clevers H.C.
Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse.
Mol. Cell. Biol. 18:1248-1256(1998)

Patent=WO1999043804A1
Barker N., Korinek V., Clevers H.C.
Mouse Tcf-3 and Tcf-4 and tumourigenesis related to wnt/wingless signalling.
Patent number WO1999043804A1, 02-Sep-1999

PubMed=11358845
Szeto W., Jiang W., Tice D.A., Rubinfeld B., Hollingshead P.G., Fong S.E., Dugger D.L., Pham T., Yansura D.G., Wong T.A., Grimaldi J.C., Corpuz R.T., Singh J.S., Frantz G.D., Devaux B., Crowley C.W., Schwall R.H., Eberhard D.A., Rastelli L., Polakis P., Pennica D.
Overexpression of the retinoic acid-responsive gene Stra6 in human cancers and its synergistic induction by Wnt-1 and retinoic acid.
Cancer Res. 61:4197-4205(2001)

PubMed=11832495; DOI=10.1074/jbc.M200334200
Tice D.A., Szeto W., Soloviev I., Rubinfeld B., Fong S.E., Dugger D.L., Winer J., Williams P.M., Wieand D., Smith V., Schwall R.H., Pennica D., Polakis P.
Synergistic induction of tumor antigens by Wnt-1 signaling and retinoic acid revealed by gene expression profiling.
J. Biol. Chem. 277:14329-14335(2002)

Cross-references
Encyclopedic resources Wikidata; Q54808204
Entry history
Entry creation15-Nov-2017
Last entry update29-Jun-2023
Version number7