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Cellosaurus ValiScreen human CRTH2 (CVCL_LC58)

[Text version]
Cell line name ValiScreen human CRTH2
Synonyms ValiScreen human prostanoid receptor DP2; CHO-CRTH2; hCRTH2-CHO
Accession CVCL_LC58
Resource Identification Initiative To cite this cell line use: ValiScreen human CRTH2 (RRID:CVCL_LC58)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; 4502; PTGDR2.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0214 (CHO-K1)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=21916510; DOI=10.1021/jm200866y
Crosignani S., Pretre A., Jorand-Lebrun C., Fraboulet G., Seenisamy J., Augustine J.K., Missotten M., Humbert Y., Cleva C., Abla N., Daff H., Schott O., Schneider M., Burgat-Charvillon F., Rivron D., Hamernig I., Arrighi J.-F., Gaudet M., Zimmerli S.C., Juillard P., Johnson Z.
Discovery of potent, selective, and orally bioavailable alkynylphenoxyacetic acid CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases.
J. Med. Chem. 54:7299-7317(2011)

Cross-references
Cell line collections (Providers) PerkinElmer; ES-561-C
Encyclopedic resources Wikidata; Q54992922
Entry history
Entry creation22-Aug-2017
Last entry update10-Sep-2024
Version number9