ID   UOK276
AC   CVCL_LC28
DR   cancercelllines; CVCL_LC28
DR   Wikidata; Q54991422
RX   PubMed=28736828;
CC   Doubling time: ~24 hours (Direct_author_submission).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.His193Tyr (c.577C>T); ClinVar=VCV000230256; Zygosity=Homozygous (PubMed=28736828).
CC   Sequence variation: Mutation; HGNC; HGNC:20456; TRAF7; Simple; p.Pro22_Thr25del; Zygosity=Homozygous; Note=Heterozygous mutation in germline of patient (PubMed=28736828).
CC   Omics: Mitochondrial genome sequenced.
CC   Miscellaneous: Doubling time from personal communication of Yang, You-Feng.
CC   Derived from site: Metastatic; Kidney; UBERON=UBERON_0002113.
ST   Source(s): PubMed=28736828
ST   Amelogenin: X,Y
ST   CSF1PO: 11
ST   D13S317: 11
ST   D16S539: 10
ST   D18S51: 13
ST   D21S11: 31
ST   D3S1358: 15
ST   D5S818: 11
ST   D7S820: 11
ST   D8S1179: 10,12
ST   FGA: 20
ST   Penta D: 10
ST   Penta E: 10
ST   TH01: 9.3
ST   TPOX: 8
ST   vWA: 16
DI   NCIt; C4146; Chromophobe renal cell carcinoma
DI   ORDO; Orphanet_319303; Chromophobe renal cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   45Y
CA   Cancer cell line
DT   Created: 22-08-17; Last updated: 19-12-24; Version: 11
//
RX   PubMed=28736828; DOI=10.1002/gcc.22476; PMCID=PMC5561006;
RA   Yang Y.-F., Vocke C.D., Ricketts C.J., Wei D., Padilla-Nash H.M.,
RA   Lang M., Sourbier C., Killian J.K., Boyle S.L., Worrell R.A.,
RA   Meltzer P.S., Ried T., Merino M.J., Metwalli A.R., Linehan W.M.;
RT   "Genomic and metabolic characterization of a chromophobe renal cell
RT   carcinoma cell line model (UOK276).";
RL   Genes Chromosomes Cancer 56:719-729(2017).
//