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Cellosaurus BeWo b30 (CVCL_LB83)

[Text version]
Cell line name BeWo b30
Synonyms BeWo clone b30; BeWo cells subclone b30
Accession CVCL_LB83
Resource Identification Initiative To cite this cell line use: BeWo b30 (RRID:CVCL_LB83)
Comments Population: Caucasian.
Characteristics: Compared to the parent cell line, forms confluent monolayers amenable to drug transport studies.
Derived from site: Metastatic; Fetal brain; UBERON=UBERON_0006238.
Disease Gestational choriocarcinoma (NCIt: C4646)
Gestational choriocarcinoma (ORDO: Orphanet_99926)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0044 (BeWo)
Sex of cell Male
Age at sampling Fetus
Category Cancer cell line
STR profile Source(s): AddexBio=C0030002/4906

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S81810,11
D7S82010,12
D13S3179,11
D16S53913,14
TH019,9.3
TPOX8
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=2153559; DOI=10.1016/0014-4827(90)90310-7
Wice B.M., Menton D., Geuze H., Schwartz A.L.
Modulators of cyclic AMP metabolism induce syncytiotrophoblast formation in vitro.
Exp. Cell Res. 186:306-316(1990)

PubMed=9374645; DOI=10.1152/ajpcell.1997.273.5.C1596
Liu F., Soares M.J., Audus K.L.
Permeability properties of monolayers of the human trophoblast cell line BeWo.
Am. J. Physiol. 273:C1596-C1604(1997)

DOI=10.1007/0-306-46861-1_8
Ganapathy V., Prasad P.D., Leibach F.H.
Choriocarcinoma.
(In book chapter) Human cell culture. Vol. 2. Cancer cell lines part 2; Masters J.R.W., Palsson B.O. (eds.); pp.141-147; Kluwer Academic Publishers; New York; USA (1999)

PubMed=18815225; DOI=10.1152/ajpcell.00286.2008; PMCID=PMC2584991
Heaton S.J., Eady J.J., Parker M.L., Gotts K.L., Dainty J.R., Fairweather-Tait S.J., McArdle H.J., Srai K.S., Elliott R.M.
The use of BeWo cells as an in vitro model for placental iron transport.
Am. J. Physiol. Cell Physiol. 295:C1445-C1453(2008)

PubMed=28724925; DOI=10.1038/s41598-017-06364-z; PMCID=PMC5517571
Rothbauer M., Patel N., Gondola H., Siwetz M., Huppertz B., Ertl P.
A comparative study of five physiological key parameters between four different human trophoblast-derived cell lines.
Sci. Rep. 7:5892-5892(2017)

Cross-references
Cell line collections (Providers) AddexBio; C0030002/4906
Encyclopedic resources Wikidata; Q54796115
Entry history
Entry creation22-Aug-2017
Last entry update10-Sep-2024
Version number11