ID   1Cc8
AC   CVCL_L893
SY   1CC8; SCC-1CC8; SC8
DR   Wikidata; Q54582811
RX   PubMed=18297114;
CC   Population: Caucasian.
CC   Selected for resistance to: DrugBank; DB00002; Cetuximab (Erbitux).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
CC   Derived from site: In situ; Oral cavity, floor of mouth; UBERON=UBERON_0003679.
DI   NCIt; C4041; Floor of mouth squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_7707 ! UM-SCC-1
SX   Male
AG   72Y
CA   Cancer cell line
DT   Created: 06-05-13; Last updated: 30-01-24; Version: 19
//
RX   PubMed=18297114; DOI=10.1038/onc.2008.19;
RA   Wheeler D.L., Huang S.-M., Kruser T.J., Nechrebecki M.M., Armstrong E.A.,
RA   Benavente S., Gondi V., Hsu K.-T., Harari P.M.;
RT   "Mechanisms of acquired resistance to cetuximab: role of HER (ErbB)
RT   family members.";
RL   Oncogene 27:3944-3956(2008).
//