ID   MM21
AC   CVCL_L790
SY   MM21-P
DR   GEO; GSM1275968
DR   GEO; GSM1275984
DR   Wikidata; Q54906078
RX   PubMed=21205078;
RX   PubMed=24916674;
CC   Population: Japanese.
CC   Doubling time: 13.9 +- 0.4 hours (PubMed=21205078).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=21205078).
CC   Sequence variation: Gene deletion; HGNC; HGNC:7773; NF2; Zygosity=Heterozygous (PubMed=21205078).
CC   Transformant: ChEBI; CHEBI_46661; Asbestos.
CC   Omics: CNV analysis.
CC   Omics: Deep exome analysis.
CC   Omics: SNP array analysis.
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C45662; Pleural epithelioid mesothelioma
DI   ORDO; Orphanet_50251; Pleural mesothelioma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   45Y
CA   Cancer cell line
DT   Created: 06-05-13; Last updated: 19-12-24; Version: 13
//
RX   PubMed=21205078; DOI=10.1111/j.1349-7006.2010.01827.x; PMCID=PMC11158380;
RA   Sato A., Torii I., Tao L.-H., Song M., Kondo N., Yoshikawa Y.,
RA   Hashimoto-Tamaoki T., Hasegawa S., Nakano T., Tsujimura T.;
RT   "Establishment of a cell line from a Japanese patient useful for
RT   generating an in vivo model of malignant pleural mesothelioma.";
RL   Cancer Sci. 102:648-655(2011).
//
RX   PubMed=24916674; DOI=10.1002/ijc.29015;
RA   Yoshikawa Y., Sato A., Tsujimura T., Otsuki T., Fukuoka K.,
RA   Hasegawa S., Nakano T., Hashimoto-Tamaoki T.;
RT   "Biallelic germline and somatic mutations in malignant mesothelioma:
RT   multiple mutations in transcription regulators including mSWI/SNF
RT   genes.";
RL   Int. J. Cancer 136:560-571(2015).
//