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Cellosaurus XP7CA (CVCL_L774)

[Text version]
Cell line name XP7CA
Synonyms Xeroderma Pigmentosum 7 CAiro; GM02997; GM2997
Accession CVCL_L774
Resource Identification Initiative To cite this cell line use: XP7CA (RRID:CVCL_L774)
Comments Population: Egyptian.
Senescence: Senesces at 22 PDL (PubMed=6492896).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Disease Xeroderma pigmentosum, complementation group C (NCIt: C114770)
Xeroderma pigmentosum (ORDO: Orphanet_910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_M224 (CW12-XPC)
Sex of cell Male
Age at sampling 4Y
Category Finite cell line
Publications

PubMed=7252263; DOI=10.1111/1523-1747.ep12479271
Cleaver J.E., Zelle B., Hashem N., El-Hefnawi M.H., German J.L. 3rd
Xeroderma pigmentosum patients from Egypt: II. Preliminary correlations of epidemiology, clinical symptoms and molecular biology.
J. Invest. Dermatol. 77:96-101(1981)

PubMed=7059984
Cleaver J.E.
Inactivation of ultraviolet repair in normal and xeroderma pigmentosum cells by methyl methanesulfonate.
Cancer Res. 42:860-863(1982)

PubMed=6492896; DOI=10.1016/0047-6374(84)90044-7
Cleaver J.E.
DNA repair deficiencies and cellular senescence are unrelated in xeroderma pigmentosum cell lines.
Mech. Ageing Dev. 27:189-196(1984)

PubMed=3030788; DOI=10.1016/0014-4827(87)90214-X
Wood C.M., Timme T.L., Hurt M.M., Brinkley B.R., Ledbetter D.H., Moses R.E.
Transformation of DNA repair-deficient human diploid fibroblasts with a simian virus 40 plasmid.
Exp. Cell Res. 169:543-553(1987)

CLPUB00447
Mulivor R.A., Suchy S.F.
1992/1993 catalog of cell lines. NIGMS human genetic mutant cell repository. 16th edition. October 1992.
(In misc. document) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda; USA (1992)

PubMed=27543334; DOI=10.1073/pnas.1610020113; PMCID=PMC5018765
Reid-Bayliss K.S., Arron S.T., Loeb L.A., Bezrookove V., Cleaver J.E.
Why Cockayne syndrome patients do not get cancer despite their DNA repair deficiency.
Proc. Natl. Acad. Sci. U.S.A. 113:10151-10156(2016)

Cross-references
Cell line collections (Providers) Coriell; GM02997
Cell line databases/resources CLO; CLO_0012584
Biological sample resources BioSample; SAMN00808205
Encyclopedic resources Wikidata; Q54837799
Entry history
Entry creation06-May-2013
Last entry update29-Jun-2023
Version number15