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Cellosaurus NUGC-3/5-FU/L (CVCL_L502)

[Text version]
Cell line name NUGC-3/5-FU/L
Synonyms NUGC-3/5FU/L; NUGC-3/5-FU; NUGC-3/5FU
Accession CVCL_L502
Resource Identification Initiative To cite this cell line use: NUGC-3/5-FU/L (RRID:CVCL_L502)
Comments Part of: JFCR45 cancer cell line panel.
Population: Japanese.
Selected for resistance to: ChEBI; CHEBI_46345; 5-fluorouracil (5-FU).
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Brachialis muscle; UBERON=UBERON_0001506.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Unspecified (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1612 (NUGC-3)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
Publications

PubMed=8609072; DOI=10.1111/j.1349-7006.1996.tb03161.x; PMCID=PMC5921054
Inaba M., Mitsuhashi J., Sawada H., Miike N., Naoe Y., Daimon A., Koizumi K., Tsujimoto H., Fukushima M.
Reduced activity of anabolizing enzymes in 5-fluorouracil-resistant human stomach cancer cells.
Jpn. J. Cancer Res. 87:212-220(1996)

PubMed=10359051; DOI=10.1111/j.1349-7006.1999.tb00754.x; PMCID=PMC5926061
Inaba M., Sawada H., Sadata A., Hamada H.
Circumvention of 5-fluorouracil resistance in human stomach cancer cells by uracil phosphoribosyltransferase gene transduction.
Jpn. J. Cancer Res. 90:349-354(1999)

PubMed=15767549; DOI=10.1158/1535-7163.MCT-04-0234
Nakatsu N., Yoshida Y., Yamazaki K., Nakamura T., Dan S., Fukui Y., Yamori T.
Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays.
Mol. Cancer Ther. 4:399-412(2005)

Cross-references
Cell line databases/resources cancercelllines; CVCL_L502
Encyclopedic resources Wikidata; Q54931162
Entry history
Entry creation06-May-2013
Last entry update19-Dec-2024
Version number18