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Cellosaurus Vogel (CVCL_L422)

[Text version]
Cell line name Vogel
Accession CVCL_L422
Resource Identification Initiative To cite this cell line use: Vogel (RRID:CVCL_L422)
Comments Part of: FACC canine tumor cell line panel.
Doubling time: 35.9 hours (PubMed=22916246).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; VGNC; VGNC:38514; BRAF; Simple; p.Val588Glu (c.1763T>A); Zygosity=Heterozygous (PubMed=27197945; PubMed=31175136).
  • Mutation; VGNC; VGNC:43120; MED12; Simple; p.Leu1349fs (c.4041_4044dupTATT); Zygosity=Heterozygous (PubMed=31175136).
  • Mutation; VGNC; VGNC:47719; TP53; Simple; p.Val162Leu (c.484G>T); Zygosity=Heterozygous (PubMed=31175136).
Disease Canine osteosarcoma (NCIt: C120045)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=27197945; PubMed=31175136

Markers:
Dog FHC2010235,239
Dog FHC2054156,172
Dog FHC2079271,275
Dog PEZ1115,119
Dog PEZ12274
Dog PEZ20176
Dog PEZ3115,131
Dog PEZ5103
Dog PEZ6176,183
Dog PEZ8228,232

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Publications

PubMed=21908323; DOI=10.1177/1040638711408064
O'Donoghue L.E., Rivest J.P., Duval D.L.
Polymerase chain reaction-based species verification and microsatellite analysis for canine cell line validation.
J. Vet. Diagn. Invest. 23:780-785(2011)

PubMed=22916246; DOI=10.1371/journal.pone.0043355; PMCID=PMC3420908
Maeda J., Yurkon C.R., Fujisawa H., Kaneko M., Genet S.C., Roybal E.J., Rota G.W., Saffer E.R., Rose B.J., Hanneman W.H., Thamm D.H., Kato T.A.
Genomic instability and telomere fusion of canine osteosarcoma cells.
PLoS ONE 7:E43355-E43355(2012)

PubMed=27197945; DOI=10.1111/vco.12192; PMCID=PMC5656225
Fowles J.S., Dailey D.D., Gustafson D.L., Thamm D.H., Duval D.L.
The Flint Animal Cancer Center (FACC) canine tumour cell line panel: a resource for veterinary drug discovery, comparative oncology and translational medicine.
Vet. Comp. Oncol. 15:481-492(2017)

PubMed=31175136; DOI=10.1158/1535-7163.MCT-18-1346; PMCID=PMC6679748
Das S., Idate R., Cronise K.E., Gustafson D.L., Duval D.L.
Identifying candidate druggable targets in canine cancer cell lines using whole-exome sequencing.
Mol. Cancer Ther. 18:1460-1471(2019)

Cross-references
Encyclopedic resources Wikidata; Q54993305
Gene expression databases GEO; GSM1974800
Entry history
Entry creation06-May-2013
Last entry update19-Dec-2024
Version number16