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Cellosaurus L-STS (CVCL_L297)

[Text version]
Cell line name L-STS
Synonyms LSTS
Accession CVCL_L297
Resource Identification Initiative To cite this cell line use: L-STS (RRID:CVCL_L297)
Comments Problematic cell line: Misclassified. Originally thought to arise from a metastatic carcinoid of the terminal ileum but shown to be an EBV-transformed lymphoblastoid cell line (PubMed=29444910; PubMed=31548718).
Doubling time: ~2 days (PubMed=19528452).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: SNP array analysis.
Derived from site: In situ; Lymph node; UBERON=UBERON_0000029.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_L296 ! H-STS
CVCL_L298 ! P-STS
Sex of cell Male
Age at sampling 42Y
Category Transformed cell line
STR profile Source(s): PubMed=29444910

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81811,12
D7S82010,12
D13S3178,13,14
D16S53912,13
D21S1128,29,30
TH016,9,9.3
TPOX8
vWA14,17,18,19

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Publications

PubMed=19528452
Pfragner R., Behmel A., Hoger H., Beham A., Ingolic E., Stelzer I., Svejda B., Moser V.A., Obenauf A.C., Siegl V., Haas O.A., Niederle B.
Establishment and characterization of three novel cell lines -- P-STS, L-STS, H-STS -- derived from a human metastatic midgut carcinoid.
Anticancer Res. 29:1951-1961(2009)

PubMed=29444910; DOI=10.1530/ERC-17-0445; PMCID=PMC5827037
Hofving T., Arvidsson Y., Almobarak B., Inge L., Pfragner R., Persson M., Stenman G., Kristiansson E., Johanson V., Nilsson O.
The neuroendocrine phenotype, genomic profile and therapeutic sensitivity of GEPNET cell lines.
Endocr. Relat. Cancer 25:367-380(2018)

PubMed=31548718; DOI=10.1038/s41588-019-0490-z
Hofving T., Karlsson J.W., Nilsson O., Nilsson J.A.
H-STS, L-STS and KRJ-I are not authentic GEPNET cell lines.
Nat. Genet. 51:1426-1427(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_L297
Encyclopedic resources Wikidata; Q54900912
Gene expression databases GEO; GSM966944
Polymorphism and mutation databases Progenetix; CVCL_L297
Entry history
Entry creation06-May-2013
Last entry update10-Sep-2024
Version number18