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Cellosaurus LNCaP-LN3 (CVCL_L162)

[Text version]
Cell line name LNCaP-LN3
Synonyms LNCaP-LN-3
Accession CVCL_L162
Resource Identification Initiative To cite this cell line use: LNCaP-LN3 (RRID:CVCL_L162)
Comments Population: Caucasian.
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
Sequence variations
  • Mutation; HGNC; HGNC:644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; HGNC:7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_L161 (LNCaP-LN2)
Children:
CVCL_L163 (LNCaP-LN4)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
Publications

PubMed=9816342
Pettaway C.A., Pathak S., Greene G., Ramirez E., Wilson M.R., Killion J.J., Fidler I.J.
Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice.
Clin. Cancer Res. 2:1627-1636(1996)

PubMed=12725112; DOI=10.1385/1-59259-372-0:21
Russell P.J., Kingsley E.A.
Human prostate cancer cell lines.
Methods Mol. Med. 81:21-39(2003)

Cross-references
Cell line collections (Providers) KCLB; 80018
Cell line databases/resources cancercelllines; CVCL_L162
Encyclopedic resources Wikidata; Q54902840
Entry history
Entry creation06-May-2013
Last entry update19-Dec-2024
Version number17