Cellosaurus cell line UM-SCC-63 (CVCL

Cellosaurus UM-SCC-63 (CVCL_L130)

Cross-references
Cell line name	UM-SCC-63
Synonyms	UMSCC-63; UMSCC 63; UMSCC63; University of Michigan-Squamous Cell Carcinoma-63
Accession	CVCL_L130
Resource Identification Initiative	To cite this cell line use: UM-SCC-63 (RRID:CVCL_L130)
Comments	Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Transformant: NCBI_TaxID; 10585; Human papillomavirus type 31 (HPV31).
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys242Phe (c.725G>T); ClinVar=VCV000376578; Zygosity=Unspecified (PubMed=1394225).
Disease	Skin squamous cell carcinoma (NCIt: C4819)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	82Y
Category	Cancer cell line
Publications	PubMed=1851275; DOI=10.1177/019459989110400304 Bradford C.R., Zacks S.E., Androphy E.J., Gregoire L., Lancaster W.D., Carey T.E. Human papillomavirus DNA sequences in cell lines derived from head and neck squamous cell carcinomas. Otolaryngol. Head Neck Surg. 104:303-310(1991) PubMed=1394225 Somers K.D., Merrick M.A., Lopez M.E., Incognito L.S., Schechter G.L., Casey G. Frequent p53 mutations in head and neck cancer. Cancer Res. 52:5997-6000(1992) PubMed=8552396 Patel A.M., Incognito L.S., Schechter G.L., Wasilenko W.J., Somers K.D. Amplification and expression of EMS-1 (cortactin) in head and neck squamous cell carcinoma cell lines. Oncogene 12:31-35(1996) PubMed=17312569; DOI=10.1002/hed.20478 Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y. Head and neck squamous cell carcinoma cell lines: established models and rationale for selection. Head Neck 29:163-188(2007)
Cell line databases/resources	cancercelllines; CVCL_L130
Encyclopedic resources	Wikidata; Q54990896
Entry history
Entry creation	06-May-2013
Last entry update	19-Dec-2024
Version number	10