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Cellosaurus YD-38 (CVCL_L083)

[Text version]
Cell line name YD-38
Synonyms YD38
Accession CVCL_L083
Resource Identification Initiative To cite this cell line use: YD-38 (RRID:CVCL_L083)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Korean.
Doubling time: 21.6 hours (PubMed=16264262).
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Oral cavity, gingiva; UBERON=UBERON_0001828.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Gly199Ter (c.595G>T); ClinVar=VCV000634672; Zygosity=Homozygous (DepMap=ACH-000762).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.56
East Asian, North61.56
East Asian, South37.62
South Asian0
European, North0
European, South0.26
Disease Gingival squamous cell carcinoma (NCIt: C129857)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 67Y
Category Cancer cell line
STR profile Source(s): KCLB=60508; PubMed=16264262

Markers:
AmelogeninX
CSF1PO12
D3S135816
D5S81814
D7S82010,11
D8S117914
D13S3178
D16S53912,13
D18S5114
D21S1130,31
FGA22,25
Penta D8,12
Penta E12,19
TH016,9
TPOX8
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=16264262; DOI=10.1038/emm.2005.48
Lee E.J., Kim J., Lee S.A., Kim E.-J., Chun Y.-C., Ryu M.H., Yook J.-I.
Characterization of newly established oral cancer cell lines derived from six squamous cell carcinoma and two mucoepidermoid carcinoma cells.
Exp. Mol. Med. 37:379-390(2005)

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=28053903; DOI=10.5125/jkaoms.2016.42.6.337; PMCID=PMC5206238
Jo D.-W., Kim Y.-K., Yun P.-Y.
The influence of p53 mutation status on the anti-cancer effect of cisplatin in oral squamous cell carcinoma cell lines.
J. Korean Assoc. Oral Maxillofac. Surg. 42:337-344(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. 3rd, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections (Providers) KCLB; 60508
Cell line databases/resources cancercelllines; CVCL_L083
Cell_Model_Passport; SIDM01412
DepMap; ACH-000762
Biological sample resources BioSample; SAMN10988077
Chemistry resources PharmacoDB; YD38_1682_2019
Encyclopedic resources Wikidata; Q54995388
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887745
GEO; GSM888840
Polymorphism and mutation databases IARC_TP53; 21621
IARC_TP53; 30220
LiGeA; CCLE_758
Progenetix; CVCL_L083
Entry history
Entry creation06-May-2013
Last entry update02-May-2024
Version number27