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Cellosaurus SNU-668-5FU (CVCL_L049)

[Text version]
Cell line name SNU-668-5FU
Synonyms SNU-668R-5-FU/4000
Accession CVCL_L049
Resource Identification Initiative To cite this cell line use: SNU-668-5FU (RRID:CVCL_L049)
Comments Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Selected for resistance to: ChEBI; CHEBI:46345; 5-fluorouracil (5-FU).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000177777; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ser215Asn (c.644G>A); ClinVar=VCV000376662; Zygosity=Homozygous (from parent cell line).
Disease Gastric signet ring cell adenocarcinoma (NCIt: C5250)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5081 (SNU-668)
Sex of cell Male
Age at sampling 63Y
Category Cancer cell line
Publications

PubMed=14734480; DOI=10.1158/1078-0432.CCR-1025-3
Kang H.C., Kim I.-J., Park J.-H., Shin Y., Ku J.-L., Jung M.S., Yoo B.C., Kim H.K., Park J.-G.
Identification of genes with differential expression in acquired drug-resistant gastric cancer cells using high-density oligonucleotide microarrays.
Clin. Cancer Res. 10:272-284(2004)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1; PMCID=PMC2785416
Ku J.-L., Park J.-G.
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

Cross-references
Cell line databases/resources cancercelllines; CVCL_L049
Encyclopedic resources Wikidata; Q54955242
Entry history
Entry creation06-May-2013
Last entry update05-Oct-2023
Version number17