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Cellosaurus WM3268 (CVCL_L031)

[Text version]
Cell line name WM3268
Synonyms WM-3268; WM 3268; WM3268V; WM-3268V; WM 3268V; WM3268A
Accession CVCL_L031
Resource Identification Initiative To cite this cell line use: WM3268 (RRID:CVCL_L031)
Comments Part of: Wistar Institute melanoma cell line collection.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (Wistar).
  • Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (Wistar).
  • Mutation; HGNC; HGNC:1097; BRAF; None_reported; -; Zygosity=- (Wistar).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (Wistar).
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX
CSF1PO11,12
D2S133817,18
D3S135813,16
D5S8189,10
D7S8209,12
D8S117913,14
D13S3178,13
D16S53911
D18S5115,18
D19S43312,13
D21S1129,32.2
FGA22,23
TH016,9.3
TPOX8,11
vWA17,18

Run an STR similarity search on this cell line
Web pages https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Hoek K.S., Schlegel N.C., Brafford P., Sucker A., Ugurel S., Kumar R., Weber B.L., Nathanson K.L., Phillips D.J., Herlyn M., Schadendorf D., Dummer R.
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=18632627; DOI=10.1158/0008-5472.CAN-08-0235; PMCID=PMC2615688
Smalley K.S.M., Contractor R., Nguyen T.K., Xiao M., Edwards R., Muthusamy V., King A.J., Flaherty K.T., Bosenberg M.W., Herlyn M., Nathanson K.L.
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Cancer Res. 68:5743-5752(2008)

Cross-references
Cell line collections (Providers) Rockland; WM3268-01-0001
Cell line databases/resources cancercelllines; CVCL_L031
Encyclopedic resources Wikidata; Q54994246
Gene expression databases GEO; GSM109038
GEO; GSM185198
GEO; GSM185199
Polymorphism and mutation databases Cosmic; 1155561
Cosmic; 1303072
Progenetix; CVCL_L031
Entry history
Entry creation06-May-2013
Last entry update19-Dec-2024
Version number19