Cellosaurus PathHunter HEK 293 PTGER4 beta-arrestin (CVCL_KZ63)
| Cell line name | PathHunter HEK 293 PTGER4 beta-arrestin |
|---|---|
| Accession | CVCL_KZ63 |
| Resource Identification Initiative | To cite this cell line use: PathHunter HEK 293 PTGER4 beta-arrestin (RRID:CVCL_KZ63) |
| Comments | Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:9596; PTGER4. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:712; ARRB2. Transformant: NCBI_TaxID; 28285; Adenovirus 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0045 (HEK293) |
| Sex of cell | Female |
| Age at sampling | Fetus |
| Category | Transformed cell line |
| Cross-references | |
| Cell line collections (Providers) | DiscoverX; 93-0304C1 |
| Encyclopedic resources | Wikidata; Q54938056 |
| Entry history | |
| Entry creation | 22-Aug-2017 |
| Last entry update | 19-Dec-2024 |
| Version number | 8 |