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Cellosaurus PathHunter HEK 293 LXRbeta-NCoR1 Protein Interaction (CVCL_KZ59)

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Cell line name PathHunter HEK 293 LXRbeta-NCoR1 Protein Interaction
Accession CVCL_KZ59
Resource Identification Initiative To cite this cell line use: PathHunter HEK 293 LXRbeta-NCoR1 Protein Interaction (RRID:CVCL_KZ59)
Comments Characteristics: PathHunter NHR protein interaction cell lines co-express a NHR tagged with a beta-galactosidase fragment (ProLink=PK) and a receptor co-activator tagged with another fragment (Enzyme Acceptor=EA). Activation of the NHR results in co-activator-EA recruitment thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:7965; NR1H2.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:7672; NCOR1.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Cross-references
Cell line collections (Providers) DiscoverX; 93-0856C1
Encyclopedic resources Wikidata; Q54938052
Entry history
Entry creation22-Aug-2017
Last entry update19-Dec-2024
Version number8