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Cellosaurus PathHunter HEK 293 FFAR1 beta-arrestin-1 (CVCL_KZ48)

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Cell line name PathHunter HEK 293 FFAR1 beta-arrestin-1
Accession CVCL_KZ48
Resource Identification Initiative To cite this cell line use: PathHunter HEK 293 FFAR1 beta-arrestin-1 (RRID:CVCL_KZ48)
Comments Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4498; FFAR1.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:711; ARRB1.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Cross-references
Cell line collections (Providers) DiscoverX; 93-0977C1
Encyclopedic resources Wikidata; Q54938029
Entry history
Entry creation22-Aug-2017
Last entry update19-Dec-2024
Version number8