Cellosaurus PathHunter HEK 293 EDG1 Total GPCR Internalization (CVCL_KZ45)
| Cell line name | PathHunter HEK 293 EDG1 Total GPCR Internalization |
|---|---|
| Synonyms | PathHunter EDG1 Total GPCR Internalization HEK 293 |
| Accession | CVCL_KZ45 |
| Resource Identification Initiative | To cite this cell line use: PathHunter HEK 293 EDG1 Total GPCR Internalization (RRID:CVCL_KZ45) |
| Comments | Characteristics: PathHunter total GPCR internalization cell lines co-express a tagged with a beta-galactosidase fragment (ProLink=PK) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the endosomes. Activation of the GPCR-PK induces internalization of the receptor in EA-tagged endosomes and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3165; S1PR1. Transformant: NCBI_TaxID; 28285; Adenovirus 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0045 (HEK293) |
| Sex of cell | Female |
| Age at sampling | Fetus |
| Category | Transformed cell line |
| Cross-references | |
| Cell line collections (Providers) | DiscoverX; 93-0784C1 |
| Encyclopedic resources | Wikidata; Q54938025 |
| Entry history | |
| Entry creation | 22-Aug-2017 |
| Last entry update | 19-Dec-2024 |
| Version number | 8 |