Cellosaurus PathHunter DLD1 MTNR1A Total GPCR Internalization (CVCL_KZ30)
Cell line name | PathHunter DLD1 MTNR1A Total GPCR Internalization |
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Synonyms | PathHunter MTNR1A Total GPCR Internalization DLD1 |
Accession | CVCL_KZ30 |
Resource Identification Initiative | To cite this cell line use: PathHunter DLD1 MTNR1A Total GPCR Internalization (RRID:CVCL_KZ30) |
Comments | Population: Caucasian. Characteristics: PathHunter total GPCR internalization cell lines co-express a tagged with a beta-galactosidase fragment (ProLink=PK) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the endosomes. Activation of the GPCR-PK induces internalization of the receptor in EA-tagged endosomes and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:7463; MTNR1A. Derived from site: In situ; Colon; UBERON=UBERON_0001155. Cell type: Epithelial cell of colon; CL=CL_0011108. |
Disease | Colon adenocarcinoma (NCIt: C4349) |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_0248 (DLD-1) |
Sex of cell | Male |
Age at sampling | 67Y |
Category | Cancer cell line |
Cross-references | |
Cell line collections (Providers) | DiscoverX; 93-0847C13 |
Encyclopedic resources | Wikidata; Q54938008 |
Entry history | |
Entry creation | 22-Aug-2017 |
Last entry update | 19-Dec-2024 |
Version number | 7 |