Cellosaurus PathHunter DLD1 MTNR1A Total GPCR Internalization (CVCL_KZ30)
| Cell line name | PathHunter DLD1 MTNR1A Total GPCR Internalization |
|---|---|
| Synonyms | PathHunter MTNR1A Total GPCR Internalization DLD1 |
| Accession | CVCL_KZ30 |
| Resource Identification Initiative | To cite this cell line use: PathHunter DLD1 MTNR1A Total GPCR Internalization (RRID:CVCL_KZ30) |
| Comments | Population: Caucasian. Characteristics: PathHunter total GPCR internalization cell lines co-express a tagged with a beta-galactosidase fragment (ProLink=PK) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the endosomes. Activation of the GPCR-PK induces internalization of the receptor in EA-tagged endosomes and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal. Genetic integration: Method=Transfection; Gene=HGNC; 7463; MTNR1A. Derived from site: In situ; Colon; UBERON=UBERON_0001155. Cell type: Epithelial cell of colon; CL=CL_0011108. |
| Disease | Colon adenocarcinoma (NCIt: C4349) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0248 (DLD-1) |
| Sex of cell | Male |
| Age at sampling | 67Y |
| Category | Cancer cell line |
| Cross-references | |
| Cell line collections (Providers) | DiscoverX; 93-0847C13 |
| Encyclopedic resources | Wikidata; Q54938008 |
| Entry history | |
| Entry creation | 22-Aug-2017 |
| Last entry update | 10-Sep-2024 |
| Version number | 6 |