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Cellosaurus PathHunter DLD1 FFAR1 beta-arrestin (CVCL_KZ27)

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Cell line name PathHunter DLD1 FFAR1 beta-arrestin
Accession CVCL_KZ27
Resource Identification Initiative To cite this cell line use: PathHunter DLD1 FFAR1 beta-arrestin (RRID:CVCL_KZ27)
Comments Population: Caucasian.
Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Genetic integration: Method=Transfection; Gene=HGNC; 4498; FFAR1.
Genetic integration: Method=Transfection; Gene=HGNC; 712; ARRB2.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Cell type: Epithelial cell of colon; CL=CL_0011108.
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0248 (DLD-1)
Sex of cell Male
Age at sampling 67Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) DiscoverX; 93-0950C13
Encyclopedic resources Wikidata; Q54938005
Entry history
Entry creation22-Aug-2017
Last entry update10-Sep-2024
Version number6