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Cellosaurus PathHunter CHO-K1 OPRM1 beta-arrestin (CVCL_KY70)

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Cell line name PathHunter CHO-K1 OPRM1 beta-arrestin
Accession CVCL_KY70
Resource Identification Initiative To cite this cell line use: PathHunter CHO-K1 OPRM1 beta-arrestin (RRID:CVCL_KY70)
Comments Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:8156; OPRM1.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:712; ARRB2.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0214 (CHO-K1)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Cross-references
Cell line collections (Providers) DiscoverX; 93-0213C2
Encyclopedic resources Wikidata; Q54937930
Entry history
Entry creation22-Aug-2017
Last entry update19-Dec-2024
Version number9