Cellosaurus PathHunter CHO-K1 mEDG3 beta-arrestin (CVCL_KY19)
Cell line name | PathHunter CHO-K1 mEDG3 beta-arrestin |
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Accession | CVCL_KY19 |
Resource Identification Initiative | To cite this cell line use: PathHunter CHO-K1 mEDG3 beta-arrestin (RRID:CVCL_KY19) |
Comments | Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal. Genetic integration: Method=Transfection; Gene=MGI; MGI:1339365; S1pr3. Genetic integration: Method=Transfection; Gene=HGNC; 712; ARRB2. Derived from site: In situ; Ovary; UBERON=UBERON_0000992. Cell type: Epithelial cell of ovary; CL=CL_2000064. |
Species of origin | Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029) |
Hierarchy | Parent: CVCL_0214 (CHO-K1) |
Sex of cell | Female |
Age at sampling | Adult |
Category | Spontaneously immortalized cell line |
Cross-references | |
Cell line collections (Providers) | DiscoverX; 93-1013C2 |
Encyclopedic resources | Wikidata; Q54937866 |
Entry history | |
Entry creation | 22-Aug-2017 |
Last entry update | 10-Sep-2024 |
Version number | 8 |