Cellosaurus PathHunter CHO-K1 CHRM4 beta-arrestin (CVCL_KW69)
| Cell line name | PathHunter CHO-K1 CHRM4 beta-arrestin |
|---|---|
| Accession | CVCL_KW69 |
| Resource Identification Initiative | To cite this cell line use: PathHunter CHO-K1 CHRM4 beta-arrestin (RRID:CVCL_KW69) |
| Comments | Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:1953; CHRM4. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:712; ARRB2. Derived from site: In situ; Ovary; UBERON=UBERON_0000992. Cell type: Epithelial cell of ovary; CL=CL_2000064. |
| Species of origin | Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029) |
| Hierarchy | Parent: CVCL_0214 (CHO-K1) |
| Sex of cell | Female |
| Age at sampling | Adult |
| Category | Spontaneously immortalized cell line |
| Cross-references | |
| Cell line collections (Providers) | DiscoverX; 93-0349C2 |
| Encyclopedic resources | Wikidata; Q54937663 |
| Entry history | |
| Entry creation | 22-Aug-2017 |
| Last entry update | 19-Dec-2024 |
| Version number | 9 |