Cellosaurus PathHunter C2C12 CXCR4 beta-arrestin (CVCL_KW18)
| Cell line name | PathHunter C2C12 CXCR4 beta-arrestin |
|---|---|
| Accession | CVCL_KW18 |
| Resource Identification Initiative | To cite this cell line use: PathHunter C2C12 CXCR4 beta-arrestin (RRID:CVCL_KW18) |
| Comments | Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:2561; CXCR4. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:712; ARRB2. Derived from site: In situ; Skeletal muscle; UBERON=UBERON_0001134. Cell type: Myoblast; CL=CL_0000056. |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: C3H. |
| Hierarchy | Parent: CVCL_0188 (C2C12) |
| Sex of cell | Female |
| Age at sampling | 2M |
| Category | Spontaneously immortalized cell line |
| Cross-references | |
| Cell line collections (Providers) | DiscoverX; 93-0203C7 |
| Encyclopedic resources | Wikidata; Q54937591 |
| Entry history | |
| Entry creation | 22-Aug-2017 |
| Last entry update | 19-Dec-2024 |
| Version number | 10 |