Cellosaurus PathHunter BHK-21 rPTGER4 beta-arrestin (CVCL_KW17)
| Cell line name | PathHunter BHK-21 rPTGER4 beta-arrestin |
|---|---|
| Accession | CVCL_KW17 |
| Resource Identification Initiative | To cite this cell line use: PathHunter BHK-21 rPTGER4 beta-arrestin (RRID:CVCL_KW17) |
| Comments | Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal. Genetic integration: Method=Transfection; Gene=RGD; 628641; Ptger4. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:712; ARRB2. Derived from site: In situ; Kidney; UBERON=UBERON_0002113. |
| Species of origin | Mesocricetus auratus (Golden hamster) (NCBI Taxonomy: 10036) |
| Hierarchy | Parent: CVCL_1915 (BHK-21 clone 13) |
| Sex of cell | Male |
| Age at sampling | 1D |
| Category | Spontaneously immortalized cell line |
| Cross-references | |
| Cell line collections (Providers) | DiscoverX; 93-0908C16 |
| Encyclopedic resources | Wikidata; Q54937590 |
| Entry history | |
| Entry creation | 22-Aug-2017 |
| Last entry update | 19-Dec-2024 |
| Version number | 8 |