Cellosaurus PathHunter A549 IkappaB Degradation (CVCL_KW16)
| Cell line name | PathHunter A549 IkappaB Degradation |
|---|---|
| Accession | CVCL_KW16 |
| Resource Identification Initiative | To cite this cell line use: PathHunter A549 IkappaB Degradation (RRID:CVCL_KW16) |
| Comments | Population: Caucasian. Characteristics: PathHunter degradation cell lines express a target protein tagged with a beta-galactosidase fragment (Enzyme Donor=ED). Pathway activation results in the degradation of the target protein. The degraded protein is detected by adding to the cell lysis buffer another beta-galactosidase fragment (Enzyme Acceptor=EA). Complementation of the ED and EA enzyme fragments result into a catalytically active enzyme that generate a chemiluminescent signal. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:7797; NFKBIA. Derived from site: In situ; Lung; UBERON=UBERON_0002048. |
| Sequence variations |
|
| Disease | Lung adenocarcinoma (NCIt: C3512) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0023 (A-549) |
| Sex of cell | Male |
| Age at sampling | 58Y |
| Category | Cancer cell line |
| Cross-references | |
| Cell line collections (Providers) | DiscoverX; 93-0538C15 |
| Cell line databases/resources | cancercelllines; CVCL_KW16 |
| Encyclopedic resources | Wikidata; Q54937588 |
| Entry history | |
| Entry creation | 22-Aug-2017 |
| Last entry update | 19-Dec-2024 |
| Version number | 12 |