Cellosaurus logo
expasy logo

Cellosaurus Saos-2 Tet-Off (CVCL_KU47)

[Text version]
Cell line name Saos-2 Tet-Off
Accession CVCL_KU47
Resource Identification Initiative To cite this cell line use: Saos-2 Tet-Off (RRID:CVCL_KU47)
Comments Population: Caucasian.
Characteristics: Transfected with the tetracycline transactivator (tTA) protein, a fusion of tetR with the activation domain of HSV-1 VP16.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (Note=With p.Met1_Arg360del).
Discontinued: Takara/Clontech; Catalog number 630911.
Discontinued: Takara/Clontech; Catalog number 631136.
Derived from site: In situ; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0548 (SaOS-2)
Sex of cell Female
Age at sampling 11Y
Category Cancer cell line
Cross-references
Encyclopedic resources Wikidata; Q54952100
Entry history
Entry creation22-Aug-2017
Last entry update19-Dec-2024
Version number13