ID   CellSensor irf1-bla TF1
AC   CVCL_KS74
SY   irf1-bla TF1; irf1-bla TF-1
DR   cancercelllines; CVCL_KS74
DR   Wikidata; Q54809191
WW   https://www.thermofisher.com/order/catalog/product/K1657
CC   Population: Japanese.
CC   Characteristics: Transfected with a plasmid containing a beta-lactamase reporter gene under control of the irf-1 response element.
CC   Characteristics: IL3 or CSF2 dependent.
CC   Sequence variation: Gene fusion; HGNC; HGNC:15868; ABHD12 + HGNC; HGNC:1537; CBFA2T3; Name(s)=CBFA2T3-ABHD12 (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Pro (c.182A>C); ClinVar=VCV000280409; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ile251Thrfs*94 (c.752delT); ClinVar=VCV001759367; Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P62593; Escherichia coli beta-lactamase bla (Note=With p.Met1_Phe22del, p.Ala23Met, p.Val82Ile and p.Met184Val).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; B.cereus Bsr.
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C7152; Erythroleukemia
DI   ORDO; Orphanet_318; Acute erythroid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0559 ! TF-1
SX   Male
AG   35Y
CA   Cancer cell line
DT   Created: 22-08-17; Last updated: 19-12-24; Version: 15
//