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Cellosaurus HLR-CREB (CVCL_KB18)

[Text version]
Cell line name HLR-CREB
Synonyms PathDetect HLR-CREB
Accession CVCL_KB18
Resource Identification Initiative To cite this cell line use: HLR-CREB (RRID:CVCL_KB18)
Comments Population: African American.
Characteristics: The luciferase reporter gene expression is under the control of a synthetic promoter containing 5 direct repeats of the 17-mer GAL4-binding site.
Characteristics: Transfected with the activation domain of CREB1 fused to the yeast GAL4 DNA-binding domain.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 2345; CREB1 (Note=With del 281-341).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P04386; Yeast GAL4 (Note=With del 148-881).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Discontinued: Agilent Technologies/Stratagene; Catalog number 800065.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_KB15 (HLR)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages https://www.chem-agilent.com/pdf/strata/800050.pdf
Publications

PubMed=11355349; DOI=10.2144/01305dd06
Hexdall L., Zheng C.-F.
Stable luciferase reporter cell lines for signal transduction pathway readout using GAL4 fusion transactivators.
BioTechniques 30:1134-1140(2001)

Cross-references
Encyclopedic resources Wikidata; Q54889863
Entry history
Entry creation22-Aug-2017
Last entry update10-Sep-2024
Version number11