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Cellosaurus CC 49 (CVCL_K141)

[Text version]
Cell line name CC 49
Synonyms CC-49; CC49
Accession CVCL_K141
Resource Identification Initiative To cite this cell line use: CC 49 (RRID:CVCL_K141)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); HB-9459.
Biotechnology: The monoclonal antibody produced by this hybridoma is known as minretumomab and has been used in phase 1 clinical trials for the treatment of various cancers.
Monoclonal antibody isotype: IgG1, kappa.
Monoclonal antibody target: Human tumor-associated glycoprotein 72 (TAG-72) (CA72-4).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2155 (P3/NS1/1-Ag4.1)
Category Hybridoma
Publications

PubMed=3396010
Muraro R., Kuroki M., Wunderlich D., Poole D.J., Colcher D., Thor A., Greiner J.W., Simpson J.F., Molinolo A.A., Noguchi P.D., Schlom J.
Generation and characterization of B72.3 second generation monoclonal antibodies reactive with the tumor-associated glycoprotein 72 antigen.
Cancer Res. 48:4588-4596(1988)

Patent=US5512443
Schlom J., Colcher D.
Second generation monoclonal antibodies having binding specificity to TAG-72 and human carcinomas and methods for employing the same.
Patent number US5512443, 30-Apr-1996

Cross-references
Cell line collections (Providers) ATCC; HB-9459
Cell line databases/resources CLO; CLO_0002214
Biological sample resources ABCD; ABCD_AJ342
Encyclopedic resources Wikidata; Q54808696
Entry history
Entry creation11-Feb-2013
Last entry update02-May-2024
Version number12