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Cellosaurus CBL-1 (CVCL_K136)

[Text version]
Cell line name CBL-1
Synonyms CBL1
Accession CVCL_K136
Resource Identification Initiative To cite this cell line use: CBL-1 (RRID:CVCL_K136)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); HB-8214.
Biotechnology: Was used to produce the monoclonal antibody gavilimomab (ABX-CBL) which was intended for use as an immunosuppressive biologic treatment of glucocorticoid-resistant graft versus host disease (Patent=US20070048305).
Monoclonal antibody isotype: IgM.
Monoclonal antibody target: UniProtKB; P35613; Human BSG/CD147.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_4032 (P3X63Ag8.653)
Category Hybridoma
Publications

PubMed=6208131; DOI=10.1089/hyb.1.1982.1.303
Billing R.J., Wells J., Zettel D., Terasaki P.I.
Monoclonal and heteroantibody reacting with different antigens common to human blast cells and monocytes.
Hybridoma 1:303-311(1982)

Patent=US5330896
Billing R.J.
Monoclonal antibodies to an autocrine growth factor antigen that binds to activated lymphocytes and cancer cells.
Patent number US5330896, 19-Jul-1994

Patent=US20070048305
Davis C.G., Blacher R.W., Corvalan J.R., Culwell A.R., Green L.L., Hales J., Havrilla N., Ivanov V.E., Lipani J.A., Liu Q., Weber R.F., Yang X.-D.
CD147 binding molecules as therapeutics.
Patent number US20070048305, 01-Mar-2007

Cross-references
Cell line collections (Providers) ATCC; HB-8214
Cell line databases/resources CLO; CLO_0002213
Biological sample resources ABCD; ABCD_AR015
Encyclopedic resources Wikidata; Q54808674
Entry history
Entry creation11-Feb-2013
Last entry update02-May-2024
Version number7