Publications | PubMed=21460823; DOI=10.1038/nmeth.1591 Okita K., Matsumura Y., Sato Y., Okada A., Morizane A., Okamoto S., Hong H.-J., Nakagawa M., Tanabe K., Tezuka K.-i., Shibata T., Kunisada T., Takahashi M., Takahashi J., Saji H., Yamanaka S. A more efficient method to generate integration-free human iPS cells. Nat. Methods 8:409-412(2011) PubMed=22802639; DOI=10.1073/pnas.1209979109; PMCID=PMC3411998 Kajiwara M., Aoi T., Okita K., Takahashi R., Inoue H., Takayama N., Endo H., Eto K., Toguchida J., Uemoto S., Yamanaka S. Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells. Proc. Natl. Acad. Sci. U.S.A. 109:12538-12543(2012) PubMed=23434393; DOI=10.1016/j.stem.2013.01.009 Kondo T., Asai M., Tsukita K., Kutoku Y., Ohsawa Y., Sunada Y., Imamura K., Egawa N., Yahata N., Okita K., Takahashi K., Asaka I., Aoi T., Watanabe A., Watanabe K., Kadoya C., Nakano R., Watanabe D., Maruyama K., Hori O., Hibino S., Choshi T., Nakahata T., Hioki H., Kaneko T., Naitoh M., Yoshikawa K., Yamawaki S., Suzuki S., Hata R., Ueno S.-i., Seki T., Kobayashi K., Toda T., Murakami K., Irie K., Klein W.L., Mori H., Asada T., Takahashi R., Iwata N., Yamanaka S., Inoue H. Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Abeta and differential drug responsiveness. Cell Stem Cell 12:487-496(2013) PubMed=24259714; DOI=10.1073/pnas.1319061110; PMCID=PMC3870695 Koyanagi-Aoi M., Ohnuki M., Takahashi K., Okita K., Noma H., Sawamura Y., Teramoto I., Narita M., Sato Y., Ichisaka T., Amano N., Watanabe A., Morizane A., Yamada Y., Sato T., Takahashi J., Yamanaka S. Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells. Proc. Natl. Acad. Sci. U.S.A. 110:20569-20574(2013) PubMed=25231866; DOI=10.1038/nature13775 Yamashita A., Morioka M., Kishi H., Kimura T., Yahara Y., Okada M., Fujita K., Sawai H., Ikegawa S., Tsumaki N. Statin treatment rescues FGFR3 skeletal dysplasia phenotypes. Nature 513:507-511(2014) PubMed=25665923; DOI=10.1016/j.scr.2015.01.007 Toyoda T., Mae S.-i., Tanaka H., Kondo Y., Funato M., Hosokawa Y., Sudo T., Kawaguchi Y., Osafune K. Cell aggregation optimizes the differentiation of human ESCs and iPSCs into pancreatic bud-like progenitor cells. Stem Cell Res. 14:185-197(2015) PubMed=26997647; DOI=10.1016/j.stemcr.2016.02.011; PMCID=PMC4834049 Ichiyanagi N., Fujimori K., Yano M., Ishihara-Fujisaki C., Sone T., Akiyama T., Okada Y., Akamatsu W., Matsumoto T., Ishikawa M., Nishimoto Y., Ishihara Y., Sakuma T., Yamamoto T., Tsuiji H., Suzuki N., Warita H., Aoki M., Okano H. Establishment of in vitro FUS-associated familial amyotrophic lateral sclerosis model using human induced pluripotent stem cells. Stem Cell Reports 6:496-510(2016) PubMed=27476965; DOI=10.1016/j.stem.2016.06.019 Nishizawa M., Chonabayashi K., Nomura M., Tanaka A., Nakamura M., Inagaki A., Nishikawa M., Takei I., Oishi A., Tanabe K., Ohnuki M., Yokota H., Koyanagi-Aoi M., Okita K., Watanabe A., Takaori-Kondo A., Yamanaka S., Yoshida Y. Epigenetic variation between human induced pluripotent stem cell lines is an indicator of differentiation capacity. Cell Stem Cell 19:341-354(2016) PubMed=30127392; DOI=10.1038/s41591-018-0140-5 Fujimori K., Ishikawa M., Otomo A., Atsuta N., Nakamura R., Akiyama T., Hadano S., Aoki M., Saya H., Sobue G., Okano H. Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent. Nat. Med. 24:1579-1589(2018) |