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Cellosaurus 90PE6E7 (CVCL_K052)

[Text version]
Cell line name 90PE6E7
Accession CVCL_K052
Resource Identification Initiative To cite this cell line use: 90PE6E7 (RRID:CVCL_K052)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
Sequence variations
  • Mutation; HGNC; HGNC:1100; BRCA1; Simple; p.Glu23Valfs*17 (c.68_69delAG) (c.66_67AG[1]) (185delAG); ClinVar=VCV000017662; Zygosity=Heterozygous (PubMed=10739701).
Disease BRCA1-associated hereditary breast and ovarian cancer syndrome (NCIt: C36100)
Hereditary breast cancer (ORDO: Orphanet_227535)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_K050 (90P)
Sex of cell Female
Age at sampling 35Y
Category Transformed cell line
Publications

PubMed=10739701; DOI=10.1006/gyno.2000.5734
Annab L.A., Terry L., Cable P.L., Brady J., Stampfer M.R., Barrett J.C., Afshari C.A.
Establishment and characterization of a breast cell strain containing a BRCA1 185delAG mutation.
Gynecol. Oncol. 77:121-128(2000)

Cross-references
Encyclopedic resources Wikidata; Q54605653
Entry history
Entry creation11-Feb-2013
Last entry update19-Dec-2024
Version number18