ID   Bruce-4
AC   CVCL_K037
SY   BRUCE-4; Bruce 4; Bruce4; BRUCE4; ES-Bruce4; EmbryoMax C57/BL6; CMTI-2
DR   EFO; EFO_0005483
DR   ENCODE; ENCBS250IKX
DR   ENCODE; ENCBS359ENC
DR   ENCODE; ENCBS551ZCI
DR   ENCODE; ENCBS855UGJ
DR   GEO; GSM769008
DR   GEO; GSM769009
DR   GEO; GSM769010
DR   GEO; GSM918748
DR   GEO; GSM918749
DR   GEO; GSM918750
DR   GEO; GSM1000089
DR   GEO; GSM1000099
DR   GEO; GSM1000109
DR   GEO; GSM1000127
DR   GEO; GSM1000147
DR   Millipore; CMTI-2
DR   Wikidata; Q54798320
RX   PubMed=8398989;
RX   PubMed=17828574;
RX   PubMed=25277546;
CC   Part of: ENCODE project mouse cell lines.
CC   Omics: H3K27ac ChIP-seq epigenome analysis.
CC   Omics: H3K27me3 ChIP-seq epigenome analysis.
CC   Omics: H3K36me3 ChIP-seq epigenome analysis.
CC   Omics: H3K4me1 ChIP-seq epigenome analysis.
CC   Omics: H3K4me3 ChIP-seq epigenome analysis.
CC   Omics: H3K9ac ChIP-seq epigenome analysis.
CC   Omics: H3K9me3 ChIP-seq epigenome analysis.
CC   Omics: SNP array analysis.
CC   Misspelling: CMT1-2; PubMed=25277546.
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
CC   Breed/subspecies: C57BL/6.Cg-Thy1.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 11-02-13; Last updated: 29-06-23; Version: 14
//
RX   PubMed=8398989; DOI=10.1093/intimm/5.8.957;
RA   Kontgen F., Suss G., Stewart C., Steinmetz M., Bluethmann H.;
RT   "Targeted disruption of the MHC class II Aa gene in C57BL/6 mice.";
RL   Int. Immunol. 5:957-964(1993).
//
RX   PubMed=17828574; DOI=10.1007/s00335-007-9054-0;
RA   Hughes E.D., Qu Y.Y., Genik S.J., Lyons R.H., Pacheco C.D.,
RA   Lieberman A.P., Samuelson L.C., Nasonkin I.O., Camper S.A.,
RA   Van Keuren M.L., Saunders T.L.;
RT   "Genetic variation in C57BL/6 ES cell lines and genetic instability in
RT   the Bruce4 C57BL/6 ES cell line.";
RL   Mamm. Genome 18:549-558(2007).
//
RX   PubMed=25277546; DOI=10.1186/1471-2164-15-847;
RA   Didion J.P., Buus R.J., Naghashfar Z., Threadgill D.W.,
RA   Morse H.C. III, Pardo-Manuel de Villena F.;
RT   "SNP array profiling of mouse cell lines identifies their strains of
RT   origin and reveals cross-contamination and widespread aneuploidy.";
RL   BMC Genomics 15:847.1-847.11(2014).
//