ID   YUAVEY
AC   CVCL_K001
DR   cancercelllines; CVCL_K001
DR   Wikidata; Q54995585
RX   PubMed=22842228;
RX   PubMed=26214590;
CC   Part of: Yale University (YU) melanoma cell collection.
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Unspecified (PubMed=26214590).
CC   Omics: Deep exome analysis.
CC   Derived from site: Metastatic; Not specified.
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   58Y
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 05-10-23; Version: 15
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RX   PubMed=22842228; DOI=10.1038/ng.2359;
RA   Krauthammer M., Kong Y., Ha B.H., Evans P., Bacchiocchi A.,
RA   McCusker J.P., Cheng E., Davis M.J., Goh G., Choi M., Ariyan S.,
RA   Narayan D., Dutton-Regester K., Capatana A., Holman E.C.,
RA   Bosenberg M.W., Sznol M., Kluger H.M., Brash D.E., Stern D.F.,
RA   Materin M.A., Lo R.S., Mane S., Ma S.-G., Kidd K.K., Hayward N.K.,
RA   Lifton R.P., Schlessinger J., Boggon T.J., Halaban R.;
RT   "Exome sequencing identifies recurrent somatic RAC1 mutations in
RT   melanoma.";
RL   Nat. Genet. 44:1006-1014(2012).
//
RX   PubMed=26214590; DOI=10.1038/ng.3361;
RA   Krauthammer M., Kong Y., Bacchiocchi A., Evans P., Pornputtapong N.,
RA   Wu C., McCusker J.P., Ma S.-G., Cheng E., Straub R., Serin M.,
RA   Bosenberg M.W., Ariyan S., Narayan D., Sznol M., Kluger H.M., Mane S.,
RA   Schlessinger J., Lifton R.P., Halaban R.;
RT   "Exome sequencing identifies recurrent mutations in NF1 and RASopathy
RT   genes in sun-exposed melanomas.";
RL   Nat. Genet. 47:996-1002(2015).
//