| Cell line name |
Jurkat-F9-1906LUC |
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| Synonyms |
J-1906-F9 |
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| Accession |
CVCL_JZ99 |
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| Resource Identification Initiative |
To cite this cell line use: Jurkat-F9-1906LUC (RRID:CVCL_JZ99) |
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| Comments |
Group: Patented cell line.
Registration: International Depositary Authority, European Collection of Cell Cultures (ECACC); 99032405.
Population: Caucasian.
Characteristics: Transfected with luciferase under the control of the PTGS2/COX-2 promoter.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084. |
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| Sequence variations |
- Mutation; HGNC; 959; BAX; Simple; p.Glu41Argfs*19 (c.121delG); ClinVar=VCV000009512; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 959; BAX; Simple; p.Glu41Glyfs*33 (c.121dupG); ClinVar=VCV000009511; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 16712; FBXW7; Simple; p.Arg505Cys (c.1513C>T); ClinVar=VCV000069961; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 6079; INPP5D; Simple; p.Gln345Ter (c.1033C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 6079; INPP5D; Simple; c.1097+1065_1097+1112del47; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 7325; MSH2; Simple; p.Arg711Ter (c.2131C>T); ClinVar=VCV000090903; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Heterozygous (from parent cell line).
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| Disease |
Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_0065 (Jurkat) |
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| Sex of cell |
Male |
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| Age at sampling |
14Y |
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| Category |
Cancer cell line |
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| Publications | Patent=WO2001004350A1
Fresno Escudero M., Iniguez-Pena M.A.
Cell line comprising the promoter of cyclooxygenase-2 (COX-2) and a witness gene, and use thereof in the search of COX-2 transcriptional induction selective inhibitors.
Patent number WO2001004350A1, 18-Jan-2001 Patent=US20040152126
Fresno Escudero M., Iniguez-Pena M.A.
Methods of screening for COX-2 inhibitors.
Patent number US20040152126, 05-Aug-2004 |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_JZ99
|
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| Encyclopedic resources |
Wikidata; Q54899155
|
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| Entry history |
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| Entry creation | 22-Aug-2017 |
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| Last entry update | 10-Sep-2024 |
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| Version number | 17 |
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