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Cellosaurus CHO dhfr(-) Bcl2 (CVCL_JZ93)

[Text version]
Cell line name CHO dhfr(-) Bcl2
Accession CVCL_JZ93
Resource Identification Initiative To cite this cell line use: CHO dhfr(-) Bcl2 (RRID:CVCL_JZ93)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Korean Collection for Type Culture; KCTC 10142BP.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:990; BCL2.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Transformant: NCIt; C44386; Gamma radiation.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
  • Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_1977 (CHO-DXB11)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

Patent=US20040014218
Lee G.M., Lee S.K.
DHFR-deficient CHO cell line transfected with an anti-apoptotic gene, method for preparation thereof, and method for producing target protein using the same.
Patent number US20040014218, 22-Jan-2004

Cross-references
Encyclopedic resources Wikidata; Q54812577
Entry history
Entry creation22-Aug-2017
Last entry update19-Dec-2024
Version number10