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Cellosaurus MDA-MB-436/GFP (CVCL_JY98)

[Text version]
Cell line name MDA-MB-436/GFP
Accession CVCL_JY98
Resource Identification Initiative To cite this cell line use: MDA-MB-436/GFP (RRID:CVCL_JY98)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Population: Caucasian.
Transfected with: UniProtKB; P42212; GFP.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; 1100; BRCA1; Simple; c.5277+1G>A; ClinVar=VCV000037654; Zygosity=Hemizygous; Note=Splice donor mutation (from parent cell line).
  • Mutation; HGNC; 9884; RB1; Simple; p.Gly203fs*9 (c.607_608ins227); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Glu204fs*7 (c.610_612delinsGCGTGTGG); Zygosity=Unspecified (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0623 (MDA-MB-436)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line
Cell line collections (Providers) Cell_Biolabs; AKR-203 - Discontinued
Cell line databases/resources cancercelllines; CVCL_JY98
Encyclopedic resources Wikidata; Q54904640
Entry history
Entry creation22-Aug-2017
Last entry update05-Oct-2023
Version number12