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Cellosaurus OVCAR-5/RFP (CVCL_JY85)

[Text version]
Cell line name OVCAR-5/RFP
Accession CVCL_JY85
Resource Identification Initiative To cite this cell line use: OVCAR-5/RFP (RRID:CVCL_JY85)
Comments Problematic cell line: Possibly misclassified. Parent cell line (OVCAR-5) was originally thought to be a high grade ovarian serous adenocarcinoma but suspected to have a upper gastrointestinal origin.
Population: Caucasian.
Transfected with: UniProtKB; Q9U6Y8; Discosoma sp. red fluorescent protein drFP583 (DsRed, RFP).
Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1628 (OVCAR-5)
Sex of cell Female
Age at sampling 67Y
Category Cancer cell line
Cell line collections (Providers) Cell_Biolabs; AKR-254
Cell line databases/resources cancercelllines; CVCL_JY85
Encyclopedic resources Wikidata; Q54937012
Entry history
Entry creation22-Aug-2017
Last entry update05-Oct-2023
Version number11