ID   H357-VB6
AC   CVCL_JY68
SY   VB6
DR   Wikidata; Q54992947
RX   PubMed=11340566;
RX   PubMed=11442751;
CC   Sequence variation: Mutation; HGNC; 5173; HRAS; Simple; p.Gly13Ser (c.37G>A); ClinVar=VCV000376323; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 6150; ITGAV.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 6161; ITGB6.
CC   Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
DI   NCIt; C4648; Tongue squamous cell carcinoma
DI   ORDO; Orphanet_457252; Squamous cell carcinoma of the oral tongue
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_JY67 ! H357-V3
SX   Male
AG   74Y
CA   Cancer cell line
DT   Created: 22-08-17; Last updated: 10-09-24; Version: 11
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RX   PubMed=11340566; DOI=10.1002/1097-0215(20010601)92:5<641::AID-IJC1243>3.0.CO;2-P;
RA   Thomas G.J., Lewis M.P., Hart I.R., Marshall J.F., Speight P.M.;
RT   "AlphaVbeta6 integrin promotes invasion of squamous carcinoma cells
RT   through up-regulation of matrix metalloproteinase-9.";
RL   Int. J. Cancer 92:641-650(2001).
//
RX   PubMed=11442751; DOI=10.1046/j.0022-202x.2001.01379.x;
RA   Thomas G.J., Lewis M.P., Whawell S.A., Russell A., Sheppard D.,
RA   Hart I.R., Speight P.M., Marshall J.F.;
RT   "Expression of the alphavbeta6 integrin promotes migration and
RT   invasion in squamous carcinoma cells.";
RL   J. Invest. Dermatol. 117:67-73(2001).
//