ID   H357-V3
AC   CVCL_JY67
SY   V3
DR   Wikidata; Q54992480
RX   PubMed=8552382;
RX   PubMed=11442751;
CC   Sequence variation: Mutation; HGNC; 5173; HRAS; Simple; p.Gly13Ser (c.37G>A); ClinVar=VCV000376323; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 6150; ITGAV.
CC   Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
DI   NCIt; C4648; Tongue squamous cell carcinoma
DI   ORDO; Orphanet_457252; Squamous cell carcinoma of the oral tongue
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2462 ! H357
SX   Male
AG   74Y
CA   Cancer cell line
DT   Created: 22-08-17; Last updated: 10-09-24; Version: 11
//
RX   PubMed=8552382;
RA   Jones J., Sugiyama M., Speight P.M., Watt F.M.;
RT   "Restoration of alpha V beta 5 integrin expression in neoplastic
RT   keratinocytes results in increased capacity for terminal
RT   differentiation and suppression of anchorage-independent growth.";
RL   Oncogene 12:119-126(1996).
//
RX   PubMed=11442751; DOI=10.1046/j.0022-202x.2001.01379.x;
RA   Thomas G.J., Lewis M.P., Whawell S.A., Russell A., Sheppard D.,
RA   Hart I.R., Speight P.M., Marshall J.F.;
RT   "Expression of the alphavbeta6 integrin promotes migration and
RT   invasion in squamous carcinoma cells.";
RL   J. Invest. Dermatol. 117:67-73(2001).
//