ID   MFD-1
AC   CVCL_JY36
DR   cancercelllines; CVCL_JY36
DR   Wikidata; Q54905377
RX   PubMed=27600491;
CC   Sequence variation: Mutation; HGNC; HGNC:40; ABCB1; Simple; p.Glu406Asp (c.1218T>G); Zygosity=Heterozygous (PubMed=27600491).
CC   Sequence variation: Mutation; HGNC; HGNC:40; ABCB1; Simple; p.Phe904Val (c.2710T>G); Zygosity=Heterozygous (PubMed=27600491).
CC   Sequence variation: Mutation; HGNC; HGNC:10736; SEMA5A; Simple; p.Lys378Arg; Zygosity=Homozygous (PubMed=27600491).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (PubMed=27600491).
CC   Omics: Chromatin accessibility by ATAC-seq.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
DI   NCIt; C4025; Esophageal adenocarcinoma
DI   ORDO; Orphanet_99976; Adenocarcinoma of the esophagus
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   55Y
CA   Cancer cell line
DT   Created: 22-08-17; Last updated: 19-12-24; Version: 14
//
RX   PubMed=27600491; DOI=10.1038/srep32417; PMCID=PMC5013399;
RA   Garcia E., Hayden A., Birts C., Britton E., Cowie A., Pickard K.,
RA   Mellone M., Choh C.T.P., Derouet M.F., Duriez P., Noble F., White M.J.,
RA   Primrose J.N., Strefford J.C., Rose-Zerilli M.J., Thomas G.J., Ang Y.S.,
RA   Sharrocks A.D., Fitzgerald R.C., Underwood T.J.;
RG   OCCAMS Consortium;
RT   "Authentication and characterisation of a new oesophageal
RT   adenocarcinoma cell line: MFD-1.";
RL   Sci. Rep. 6:32417-32417(2016).
//