Cellosaurus cell line 12370 (CVCL

Cellosaurus 12370 (CVCL_JY27)

[Text version]

Cell line name

12370

Accession

CVCL_JY27

Resource Identification Initiative

To cite this cell line use: 12370 (RRID:CVCL_JY27)

Comments

Doubling time: 6-9 days (PubMed=25862976).
Omics: Genome sequenced (low read coverage).
Omics: Transcriptome analysis by RNAseq.
Miscellaneous: Age at sampling from personal communication of Castillo-Tong, Dan Cacsire.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.

Sequence variations

Mutation; HGNC; HGNC:11998; TP53; Simple; p.His193Pro (c.578A>C); ClinVar=VCV000376612; Zygosity=Unspecified (PubMed=25862976; PubMed=31150822).

Disease

High grade ovarian serous adenocarcinoma (NCIt: C105555)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

67Y

Category

Cancer cell line

STR profile

Source(s): PubMed=31150822

Markers:

Amelogenin	X
CSF1PO	11
D1S1656	17.3
D2S1338	19,23
D3S1358	14,17
D5S818	10,11
D6S1043	13
D7S820	7,8
D8S1179	12,13
D12S391	17
D13S317	12
D16S539	12
D18S51	14,17
D19S433	14,15
D21S11	28,29
FGA	20
Penta D	11,13
Penta E	7,9
TH01	9.3
TPOX	8
vWA	15

Publications

PubMed=25862976; DOI=10.1016/j.canlet.2015.03.040
Kreuzinger C., Gamperl M., Wolf A., Heinze G., Geroldinger A., Lambrechts D., Boeckx B., Smeets D., Horvat R., Aust S., Hamilton G., Zeillinger R., Castillo-Tong D.C.
Molecular characterization of 7 new established cell lines from high grade serous ovarian cancer.
Cancer Lett. 362:218-228(2015)

PubMed=31150822; DOI=10.1016/j.canlet.2019.05.032
Kreuzinger C., von der Decken I., Wolf A., Gamperl M., Koller J., Karacs J., Pfaffinger S., Bartl T., Reinthaller A., Grimm C., Singer C.F., Braicu E.I., Cunnea P., Gourley C., Smeets D., Boeckx B., Lambrechts D., Perco P., Horvat R., Berns E.M.J.J., Castillo-Tong D.C.
Patient-derived cell line models revealed therapeutic targets and molecular mechanisms underlying disease progression of high grade serous ovarian cancer.
Cancer Lett. 459:1-12(2019)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_JY27

Encyclopedic resources

Wikidata; Q54581195

Entry history

Entry creation

22-Aug-2017

Last entry update

19-Dec-2024

Version number