ID   PC12h
AC   CVCL_JX88
SY   PC-12h; PC 12h; PC12 subclone h
DR   Wikidata; Q54938546
RX   PubMed=2246260;
RX   PubMed=6116517;
RX   PubMed=6286607;
RX   PubMed=7530581;
CC   Characteristics: Shows NGF-mediated increase of tyrosine hydroxlyase activity.
CC   Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
CC   Breed/subspecies: NEDH.
DI   NCIt; C121568; Rat adrenal gland pheochromocytoma
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_0481 ! PC12
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 22-08-17; Last updated: 29-06-23; Version: 7
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RX   PubMed=2246260; DOI=10.1016/S0021-9258(17)45440-8;
RA   Ikenaka K., Nakahira K., Takayama C., Wada K., Hatanaka H.,
RA   Mikoshiba K.;
RT   "Nerve growth factor rapidly induces expression of the 68-kDa
RT   neurofilament gene by posttranscriptional modification in PC12h-R
RT   cells.";
RL   J. Biol. Chem. 265:19782-19785(1990).
//
RX   PubMed=6116517; DOI=10.1016/0006-8993(81)91029-5;
RA   Hatanaka H.;
RT   "Nerve growth factor-mediated stimulation of tyrosine hydroxylase
RT   activity in a clonal rat pheochromocytoma cell line.";
RL   Brain Res. 222:225-233(1981).
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RX   PubMed=6286607; DOI=10.1016/S0021-9258(18)34054-7;
RA   Inoue N., Hatanaka H.;
RT   "Nerve growth factor induces specific enkephalin binding sites in a
RT   nerve cell line.";
RL   J. Biol. Chem. 257:9238-9241(1982).
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RX   PubMed=7530581; DOI=10.1016/0006-8993(94)91190-8;
RA   Yamada M., Ikeuchi T., Tsukui H., Aimoto S., Hatanaka H.;
RT   "Sustained tyrosine phosphorylation of p140trkA in PC12h-R cells
RT   responding rapidly to NGF.";
RL   Brain Res. 661:137-146(1994).
//