Cellosaurus TTNT-1 (CVCL_JX67)
| Cell line name | TTNT-1 |
|---|---|
| Accession | CVCL_JX67 |
| Resource Identification Initiative | To cite this cell line use: TTNT-1 (RRID:CVCL_JX67) |
| Comments | Group: Patented cell line. Registration: International Depositary Authority, Japanese National Institute of Bioscience and Human-Technology, Agency of Industrial Science and Technology; FERM BP-7498. Characteristics: Because it has been transduced by a construct containing LoxP sites, transfection with the Cre recombinase eliminates the SV40 T gene thus reverting the cells to a non-immortal phenotype. Characteristics: Transduced with a retroviral vector SSR#197 (MoMLV/LTR-LoxP-hTERT-IRES-EGFP-LoxP-MoMLV/LTR) expressing hTERT and eGFP flanked by a pair of loxP sites. Transfected with: HGNC; 11730; TERT. Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP). Derived from site: In situ; Liver; UBERON=UBERON_0002107. Cell type: Hepatocyte; CL=CL_0000182. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Sex of cell | Sex unspecified |
| Age at sampling | Adult |
| Category | Telomerase immortalized cell line |
| Publications | Patent=US7521234 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q54973294 |
| Entry history | |
| Entry creation | 22-Aug-2017 |
| Last entry update | 29-Jun-2023 |
| Version number | 6 |